Bio-informatics for the neuroscientist #BIN

September 21 to October 2 (2015)

Many different disciplines are engaged in neuroscience, from neurophysiology and structural biology to psychiatry and linguistics. They provide each important data, however, reported in a very different format. It becomes increasingly important to be able to retrieve information from this entire multidisciplinary arena through available databases. The well-developed area of Bioinformatics extending from genes to the cellular level, should interface directly with neuroinformatics with its focus on neuroscience, which also includes the systems level and disease mechanisms. The Cajal Advanced Neuroscience Training “Bioinformatics for the neuroscience” will provide students with a practical knowledge of state of the art bioinformatics and modelling methods used to understand the molecular and cellular basis of neuronal functions and pathologies. The course will feature introductory lectures about theory and tools, practical hands on sessions, and scientific seminars illustrating how bioinformatics answered specific neurobiological questions. We will cover genomics, epigenetics, functional genomics, biological pathways and models of biochemistry and electrophysiology of single neurons.

Course director & co-directors

  • Nicolas Le Novère (Babraham Institute, UK)
  • Marie-Claude Potier (Sorbonne University Paris, France)
  • Macha Nikolski (Bordeaux Neurocampus, France)

Aurélien Barré (Bordeaux Bioinformatics Center, France)
Sandrine Caburet (Institut Jacques Monod, France)
Claudine Chaouiya (Gulbenkian Institute of Science, Portugal)
Benjamin Dartigues (Bordeaux Bioinformatics Center, France)
Frédéric Lemoine (Institut du Cerveau et de la Moëlle épinière, France)
Ivan Moszer (Institut du Cerveau et de la Moëlle épinière, France)
Hayssam Soueidan (Bordeaux Bioinformatics Center, France)
Raluca Uricaru (Bordeaux Bioinformatics Center, France)

  • Foundational knowledge: usage of R, manipulation of large amount of NGS data
  • Genomics: genome databases, Ensembl, genome wide association studies
  • Epigenetics: DNA methylation, histone marks, bisulfite sequencing and ChIP-seq
  • Functional genomics: analysis of RNA-seq data, Expression atlas, Gene Ontology and pathway enrichment
  • Proteomics, metabolomics: basic principles of mass-spectrometry and NMR, relevant databases, synaptic proteome
  • Network biology: Network inference, Interactomes and pathways databases, Cytoscape, network enrichment

Keynote speakers

Julio Banga (Instituto Investigationes Marinas, Spain)
Sven Bergmann
(University of Lausanne, Switzerland)
Laura Furlong
(Pompeu Fabra University, Spain)
Padraig Gleeson
(University College London, UK)
Pierre de la Grange
(Genosplice, France)
Justine Guégan
(Institut du Cerveau et de la Moëlle épinière, France)
Christophe Junot
(CEA, France)
Olivier Kirsh
(University Paris Diderot, France)
Reiner Veitia
(Institut Jacques Monod, France)
Alejandro Villaverde
(Instituto Investigationes Marinas, Spain)